Yuu Stine wakes up with a few others in their school inside a locked decrepit classroom. After escaping, their group quickly discovers that the entire high school was under lockdown, with no one allowed to leave school grounds. However, that is the least of their problems. After all, their schoolmates are all a bunch of bloodthirsty cannibals infected with a disease known as "Magic".

Luckily, there is a cure. Yuu's blood tastes like sugar and, if treated, her blood will cure the hunger the infected students feel. Unfortunately, Yuu and her friends get captured. In order to save them, Yuu sacrifices herself, leading their captives away. While the others escaped, Yuu's luck seemed to run out when she ran into the lair of Jill, a student feared by all for her skill in battle and crazed mind. To make matters worse, Yuu's group ran into Jill before and, to make a long story short, pissed her off.

Yet, upon meeting Jill, Yuu doesn't get ripped to shreds or made into snacks. Instead, the two form an unlikely alliance. Still, can even such a relationship work out? Jill is an insane cannibal who feels the hunger more than everyone except for one other person, and Yuu is someone who can't quite wrap her mind around the horrors that are going on and may break if put under too much pressure.

But, with no end to the hunger near, these two are ready to survive whatever their twisted world has to throw at them.